Psilocybin is the major psychoactive compound present in magic mushrooms. Much like cannabis, psilocybin is classified as a Schedule 1 controlled substance with no medical purpose. However, recent studies have identified important medical effects of psilocybin. One area where psilocybin has been purported to affect is in the treatment of depression. The beneficial compound has been approved on two occasions for trials regarding depression by the FDA. The first trial for the compound was for severe treatment-resistant depression. The second approval was directed towards major depressive disorder. Major depressive disorder is a very common condition with over 300 million suffering from the condition.