The ability to predict the effect of a CBD product is largely dependent on the dose of cannabinoids present. CBD acts through the cannabinoid receptors of the endocannabinoid system to mediate different responses, therefore accuracy of the dose is needed to predict the response to expect. This response is then used to establish a dose-response relationship to prevent unwanted effects of underdose or overdose. The established dose, therefore, becomes a point of reference for other cannabis strains that have different cannabinoid profiles. It also becomes a point of reference for other brands in the industry to work on.