Each of the four States has peculiarities in terms of their road to legalization. Kansas already had two medical marijuana bills squashed last year. Nonetheless, the journey of West Virginia to medical marijuana legalization in 2017 leaves much to expect good news in Kansas too. Though the stakeholders in some of these states seem resilient with prohibition, they will have no choice in the face of a decision made by voters. This was the case of Mississippi where voters used the power of the ballot box to incorporate medical marijuana despite resistance from the legislature.