More than one in 10 high school seniors reported recent use of products with delta 8 THC, according to the results of a study published this week. The study found that approximately 11% of 12th-grade students said that they had used delta 8 during the past year, reflecting the widespread availability of the hemp-derived cannabinoid that is sometimes referred to as “diet weed” or “light THC.”

The new research analyzed data from the Monitoring the Future survey, an ongoing study of the behaviors, attitudes and values of adolescents and young adults funded by the National Institutes of Health. The analysis showed that 11.4% of high school seniors had used delta 8 THC products in the last year. Of the 295 teens who reported using the compound, more than two-thirds (68.1%) said they had used it at least three times, while 35.4% had used it at least 10 times and nearly 17% used it at least 40 times. Nine out of 10 (91%) of delta 8 users also said that they used marijuana.

“Eleven percent is a lot of people — that’s at least one or two students in every average-sized high school class who may be using delta-8. We don’t know enough about these drugs, but we see that they are already extremely accessible to teens,” Nora Volkow, director of the National Institute on Drug Abuse, said in a statement about the research from the agency. “Cannabis use in general has been associated with negative impacts on the adolescent brain, so we must pay attention to the kinds of cannabis products teens are using, educate young people about potential risks, and ensure that treatment for cannabis use disorder and adequate mental health care is provided to those who need it.”

Delta 8 And The 2018 Farm Bill

The popularity of delta 8 THC skyrocketed after the 2018 Farm Bill legalized hemp at the federal level. Unregulated Delta 8 products were soon available at retailers including convenience stores, gas stations and smoke shops. Delta 8 products are particularly popular in states that have not legalized marijuana for recreational use, a trend that was reflected in data from the new study. About 14% of those in states without cannabis legalization reported delta 8 use, compared to 8% in states with legalization.

Dr. Adam Leventhal, executive director of the USC Institute for Addiction Science and one of the authors of the study, said that the new research illustrates how widely available delta 8 products are to young people.

“What we hadn’t known prior to this study was to what extent are these products reaching teens, which was a concern because they weren’t being comprehensively regulated,” Leventhal told CNN.

The researchers expressed concern that the widespread use of delta 8 by teenagers could lead to developmental issues or other negative effects. The long-term effects of delta 8 THC on teens are not known, although some cannabis research has shown that the drug can negatively impact memory, attention and the ability to learn in young people.

“Some of the concerns based on the underlying biology would be, of course, addiction, like what we see with marijuana, some of the neurodevelopmental changes that can happen because the adolescent brain is still forming and exposure to intoxicating substances can interfere with proper development of the brain pathways that support cognition and emotion regulation,” Leventhal said.

Jonathan Miller, the general counsel for the U.S. Hemp Roundtable, a trade group representing businesses in the hemp industry, said the results of the study were “shocking, but it’s not surprising.”

“Our hemp industry is filled with actors who provide good manufacturing practices and truth in labeling and make good efforts to keep intoxicating products out of the hands of minors, but there are unfortunately a lot of bad actors out there,” Miller said in a phone interview on Wednesday. “But the worst actor of all in this is the FDA. The FDA said when the farm bill passed in 2018 that it would take steps to start regulating hemp products and they’ve done nothing. And as a result, we’ve got a wild west.”

Miller noted that several states are taking action to regulate delta 8 THC, citing Kentucky as a state taking strong measures to keep intoxicating hemp cannabinoids out of the hands of young people. Until the FDA takes action, it will be up to states to pass rules governing hemp cannabinoids, leaving conscientious businesses with a murky regulatory environment to operate in.

Shawn Hauser, a partner at the cannabis and psychedelics law firm Vicente LLP and co-chair of the practice’s Hemp and Cannabinoids Department, said the study’s findings “illustrate the urgent need to federally legalize all cannabis (marijuana and hemp-derived products) with fundamental product safety standards governing product manufacturing, testing, labeling, marketing, etc.”

“The hemp market, which is particularly robust in states without marijuana programs, has inflamed the need for federal legalization of all cannabis products that equip state and federal regulators to appropriately protect consumer safety through regulation, enforcement, and consumer education,” Hauser wrote in an email to High Times. “Regulation is more effective than prohibition in keeping cannabis out of the hands of children.”

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The hemp-derived cannabinoid market is hotter than ever but experts warn that people should educate themselves about the fundamental differences between delta-8 THC and delta-9 THC products. High Times previously reported that delta-8 THC was first partially synthesized in 1941, yet there’s still a lot of controversy surrounding the ingredient, due to the way it’s extracted and converted. 

Nextar reports that a Johns Hopkins School of Medicine professor and other experts want to educate people about the choices they should make with cannabis.

“Chemically, they’re almost identical. But that one little difference in that chemical structure results in a different way that it interacts with your body … with your [cannabinoid] receptors,” explains Ryan Vandrey, Ph.D., a professor at the Johns Hopkins School of Medicine who specializes in the behavior pharmacology of cannabis.

The majority of delta-8 on the market is converted from CBD, using a natural solvent and an acid as a catalyst, but people inside and out of the cannabis industry cannot seem to agree whether delta-8 should be defined as synthetic or natural. 

Vandrey also added that delta-9 THC is stronger, so why would consumers go to delta-8?

“The reason people call delta-8-THC ‘diet weed’ [is because] that chemical difference is a little less potent at what it does at the receptor,” Vandrey said, adding that delta-8 is “about half as effective” at producing the same high as delta-9.

“Does delta-8 THC get you high or is it a scam?” a popular Reddit thread in r/weed asked. The consensus appears to confirm that it has fewer psychedelic effects compared to delta-9 THC.

Sales of hemp-derived cannabinoids like CBD outpace adult-use cannabis and are comparable to the craft beer industry, Whitney Economics found. There are no signs that the industry is going to slow down.

Representatives from NORML have told High Times that delta-8 is not a primary concern, but it’s more about residual chemicals and other byproducts in gas station hemp products you should be worried about most. Dale Gieringer of Cal NORML specifically warned about THCO, which he thinks is instead one of the more particularly problematic compounds with the potential for real injuries.

Peter Grinspoon, M.D.,a primary care doctor at Mass General Hospital and an instructor at Harvard Medical School, supports medical cannabis but says state medical cannabis programs do a much better job at vetting ingredients than shops selling delta-8 products.

Grinspoon clarified that the confusion caused by the federal government itself makes it hard to distinguish what’s safe and what’s not regarding hemp-derived cannabinoids.

“In addition to lack of regulation, we have regulatory incoherence from different branches and levels of government. … That’s going to make it even harder to get any coherent regulation on things,” he told Nexstar.

Legal experts noted that the FDA had no intention of legalizing delta-8 when the 2018 Farm Bill was passed, so time’s ticking for the hemp-derived cannabinoids industry. But sellers have it practically everywhere.

“Delta-8 is so close to delta-9, it’s probably relatively safe,” Grinspoon said. “But even if we figured out that delta-8 is safe—the delta-8 you’re buying at your local smoke shop, we have no idea what’s in it.”

The 2018 Farm Bill paved the way for the Ninth Circuit Court to rule that certain low-THC cannabis derivatives were exempt from the Controlled Substances Act. This left a loophole for hemp-derived products that produce a psychoactive effect, but the feds never intended to do so.

The Food and Drug Administration (FDA) warned that delta-8 and similar cannabinoid derivatives, have “psychoactive and intoxicating effects that may be dangerous to consumers” and urged Congress to act and set up regulations. These hemp-derived cannabinoids leave room for the potential of harmful contaminants, the FDA says.

How is Delta-8 THC Made?

Delta-8 THC is only found in minute amounts in the wild, therefore in order to get enough to infuse products, it must be converted from CBD. Roger Adams and a team of researchers at the University of Illinois were the first to report partial synthesis of delta-8 in 1941.

High Times reported on exactly how it’s done:

The publication Chemical and Engineering News (CEN) described the process as “refluxing CBD in an organic solvent, such as toluene or heptane, with p-toluenesulfonic acid or another acid that serves as a catalyst.” In a controlled, regulated environment, these reactions would be done by PhD chemists to ensure there are no harmful by-products left in products sold to consumers, but the hemp industry is notoriously under-regulated with no requirements for lab testing.

CEN also described the rise of delta-8 THC “a concern.”

It’s up to every consumer to adhere to “buyer beware,” or at least know the differences between delta-8 and delta-9 THC, which are significant.

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