There are limited CB1 and CB2 receptors in the liver, but there are higher amounts in diseased livers than in healthy ones. Scientists suggest that these receptors are vital to the regeneration process of scarred tissues in the organ. Parfieniuk and Flisaik explained this complex process in a 2008 study. The scientists proposed that the receptors have opposing roles. CB1 functions as a profibrogenic and proinflammatory compound, while CB2 opposes these functions.
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