Colorado’s trailblazing journey toward the legalization of psychedelics has reached a significant turning point with the formal establishment of a complete set of laws for the state’s burgeoning psilocybin business. After nearly two years of meticulous planning, this regulatory framework allows businesses to engage in the manufacturing, distribution, and therapeutic use of mescaline, psilocin, ibogaine, DMT, and magic mushrooms as allowed by Proposition 122.