Our own endocannabinoid system feeds on omega-3 fatty acids so in the human body, they work extremely well together. The endocannabinoid system is much more regulated with adequate omega-3 fatty acid levels in the body, and enables it to metabolize cannabidiol (CBD), tetrahydrocannabinol (THC), and all the many other valuable cannabinoids in the plant that help us heal and stabilize our own systems. It’s also important to note that the active ingredients within the cannabis plant are fat-soluble, which means that they need fat to properly metabolize (this is also why cannabinoids bind so well to fat when making edibles!).