The Rhesus monkeys were first administered 131 to 3150 mg/kg of THC or 5,000 mg/kg of CME. None of the monkeys used died from this dose. The scientists then increased the THC doses to about 9,000 mg/kg in an attempt to figure out just how much THC can kill a primate. This still proved to be insufficient enough to kill the animals. The animals were however very affected by the high amounts of THC they were administered. The expressed behavior changes that affected their moods. According to the researchers, several of these animals showed signs of depression, imbalance, drowsiness, lack of coordination, lethargy, and an obvious change in posture. About 90% of the treated primates took up a huddled posture often facing the back of their cases, with their heads and hands placed between their legs.