After 12 months, 70% of the participants still had antidepressant responses while over half were in remission. “Psilocybin not only produces significant and immediate effects, it also has a long duration which suggests that it may be uniquely useful new treatment for depression,” explains Roland Griffiths, PhD. “Compared to standard antidepressants, which must be taken for long stretches of time, psilocybin has the potential to enduringly relieve the symptoms of depression with one or two treatments,” he adds.