As debates over cannabis reform continue across the globe, Uruguay remains the only country with more than a decade of real-world data on full adult-use legalization. That milestone took on new significance this year with the death of José “Pepe” Mujica, the former president who championed the world’s first national legalization framework.
Mujica’s law, passed in 2013, was never about profit. It aimed to dismantle hypocrisy, protect public health and reduce the harms of prohibition. Today, his vision lives on through Uruguay’s cannabis system, which continues to evolve and offer insights to countries still grappling with reform.
At C-Days 2025, a global cannabis and psychedelics summit held in Barcelona, Mercedes Ponce de León, founder of Latinnabis and director of Expo Cannabis Uruguay, presented a data-driven update on Uruguay’s cannabis model: what has worked, where challenges remain and what the world can learn from it.
Uruguay’s adult-use system allows for three legal pathways to access cannabis:
As of early 2025, 102,125 users were officially registered through these channels:
The country has over 460 licensed clubs and 40 pharmacies participating in the program.
Pharmacies remain the most common access point, offering four strains with distinct THC and CBD profiles. Cannabis is sold in sealed 5-gram packs, with prices set by the government:
| Strain | %THC | %CBD | Psychoactivity | Price (UYU) | Approx. USD |
|---|---|---|---|---|---|
| Alfa | ≤9 | ≥3 | Medium/Low | $470 | $11.24 |
| Beta | ≤9 | ≥3 | Medium/Low | $490 | $11.71 |
| Gamma | ≤15 | ≤1 | High | $550 | $13.15 |
| Épsilon | ≤20 | ≤1 | High | $600 | $14.34 |
Despite widespread access, restrictions on potency, product format and availability continue to limit impact and consumer satisfaction, Ponce de León noted.
Yes, but not without caveats. According to official data presented at C-Days:
Uruguay’s 2024 National Drug Survey showed that 37% of cannabis users now access the plant through legal means.
Despite positive public health outcomes, the model faces persistent challenges:
Ponce de León outlined four priorities for 2025 and beyond:
Uruguay did what many countries are still debating. It built a legal cannabis system that reduces harm, shrinks the illicit market and respects consumer rights. The outcomes are measurable. So are the gaps.
In Ponce de León’s words:
“The positive impact is proven. But if the framework isn’t updated, if access doesn’t expand and innovation isn’t guaranteed, the model risks becoming symbolic rather than functional.”
As the world reflects on the legacy of José “Pepe” Mujica, Uruguay’s cannabis experiment remains part of his lasting imprint on history. The road ahead will determine whether that legacy deepens or stalls.
Via El Planteo
Photo by Jared Schwitzke on Unsplash.
The post What Happens After Adult-Use Legalization? Uruguay’s 10-Year Cannabis Report Card first appeared on High Times.
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