We know that the phytocannabinoids like THC and CBD, plus other cannabinoids frequently discovered, have therapeutic effects. We also know that our endocannabinoid system has receptors throughout the body that interact with the phytocannabinoids. This rather complex phenomenon involves endogenous and exogenous ligands and cross-reactions. When it comes to arthritis-related pain, the endocannabinoid system together with the cannabinoids derived from cannabis plays a major role in pain reduction. The human synovial fluid from arthritis joints contains anandamide and 2-arachidonyl glycerol, meaning that these endocannabinoids are synthesized when tissue is damaged.
Members of Outlawz have said for years that they mixed some of Tupac Shakur’s ashes…
State and local police made at least 218,152 marijuana-related arrests in 2025, including 200,960 for…
Three days in Philadelphia, September 25 to 27, with a free record-clearing clinic and a…
Four decades after its Amsterdam beginnings, Barney’s Farm is marking the milestone with new markets,…
Gallup’s new numbers hold a small, awkward pattern: the Americans most convinced cannabis is bad…
The FDA is seeking outside data and analytics services to better understand how people use…