Anandamide has unique traits and activities that help the ECS have a beneficial relationship with plant-derived cannabis plants. It wasn’t discovered until the early 1900s, around the exact time THC, CBD, and other phytocannabinoids were discovered. Subsequently, science journals suggested that phytocannabinoids could bind to natural receptors in the human body to showcase their impacts. Between 1990 and 1995, Dr. Rapheal Mecholam and his research team reported successfully isolating anandamide from the human brain.